Exact(3)
The principles will be reversed to the following checkpoints: 1.
Our data suggest that the actin cytoskeleton may contribute to monospermy at two checkpoints: (1) by restricting the number of sperm-egg interaction sites on the egg surface, (2) by transmitting the dynamic rearrangement of cortical actin fibers to the entire egg sphere.
∆SpO2, the difference between checkpoints 1 and 4 (SpO2 at checkpoint 1 – SpO2 at checkpoint 4).
Similar(57)
Biochemical and genetic studies have demonstrated Chk1 to be essential and indispensable for the S- and G2/M checkpoints [ 1, 8].
On the other hand therapeutic concentrations of DOX induces cell arrest at G2/M and/or G1/S checkpoints [ 47, 48].
Although p53 status could influence DNA damage and cell cycle checkpoints, p53 mutation was not a determinant of resistance.
Early studies utilizing cell lines established the dependence of transition from G0/G1 into the S phase upon CDK 4, 6, and 2-controlled checkpoints [1].
Thereby, they are omitting important cell cycle checkpoints [40], [41].
Cytoskeletal dynamics and polarization during NK cell cytotoxicity provides a series of checkpoints [10].
Several mechanisms have been proposed to explain this phenomena, including overriding checkpoints [8].
nmt1 pyp3 mik1Δ cells lack the cell-cycle arrest function because they lack both G2 targets of the checkpoints [12].
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