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Sentries of old might have considered the requirement for someone to whisper the word "Methuselah" to get past a checkpoint to be pretty damn stringent, but as soon as "Methuselah" was forgotten or passed on (deliberately or inadvertently), they may as well have abandoned the checkpoint and put up a sign saying: "Come on in".
Since we set the threshold at the G1/S checkpoint to be smaller than that at other checkpoints, G1 arrested cells accumulated in the population more than other arrested cells.
I think what is confusing us is that if Baz is necessary for the checkpoint to be satisfied, then the checkpoint should never be satisfied whether or not the spindle is correctly oriented, and so what we would have expected is fewer spindles, period, but the fraction of spindles that were mis-oriented should be the same as when Baz is present.
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When the Afghan Army arrived, soldiers pushed the Taliban back, allowing the checkpoints to be re-established.
For example, the necessary and sufficient conditions for a set of checkpoints to be part of a consistent global checkpoint has been established for distributed computations.
Larmer suggests requiring each student to do specific tasks when working on a team product and have checkpoints to be sure this is happening.
There are checkpoints to be sure, but what 'securing' an area actually means is sending marines on door to door raids of an area, often in the dead of night.
The G2/M checkpoint appears to be established through two distinct steps: immediate establishment of the checkpoint, and maintenance of prolonged arrest (Taylor and Stark, 2001).
Meanwhile, the Syndicate rendezvous at a checkpoint, preparing to be taken away by the Colonists, who are prepping for invasion.
CTLA-4 was the first negative regulatory checkpoint receptor to be clinically targeted.
Therefore, the checkpoint appeared to be functional in cenp-metaΔ mutant cells.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com