Police officials said the councilman had waved Mr. Askew, a political opponent, through a security checkpoint that required visitors, but not elected officials, to pass through a metal detector.
have challenged this view as Drosophila p53 is able regulate cell cycle upon energy deprivation: the "tenured" mutation disrupts the mitochondrial electron transport chain and causes reduced cellular ATP level, which leads to a G1/S checkpoint arrest that requires Dmp53 [ 12].
Baleen It's the rare restaurant that requires you to pass a security checkpoint, but that's the drill at Baleen, which opened last year in the Grove Isle Club and Resort in Coconut Grove.
Mitotic catastrophe can be the result of unsuccessful chromosome segregation, an event that requires malfunctioning of multiple cell cycle checkpoints.
We further show that establishment of FHL2-null cell lines differs from conventional immortalization scheme by retaining functional p19ARF/p53 checkpoint that is required for cell cycle arrest imposed by Ras.
Previous studies have established that the hydrolysis of ATP is required to disassemble the checkpoint effector (Miniowitz-Shemtov et al., 2010): hydrolysis of ATP releases energy, but the specific steps that require this energy had not been identified.
We noticed that checkpoint behavior requires that the dissociation of the MCC APC is regulated by microtubule attachment.
While the B complex does not appear to be involved in the transient G2-M checkpoint control [ 76], it is required for G2-accumulation checkpoint that is also observed for BRCA1-deficient cells [ 29, 76, 114].
Overall, our data suggest a model in which Plx1 is required for modulating the intra-S-phase checkpoint that regulates DNA replication progression in an embryonic model system.
Earlier, it was found that Bach1 is required for progression through S phase [ 77] and is required for cell cycle checkpoint that accumulates cells at G2 phase (G2 accumulation) after DNA damage [ 29, 76].
