Sentence examples for checkpoint status from inspiring English sources

A cellular pharmacology study (cytotoxicity, apoptosis, cellular drug accumulation, DNA damage, and cell cycle perturbation) was performed in DU145 and PC3 cells, characterized by a different cell cycle checkpoint status.

Both genes are essential in maintaining the DN3 checkpoint status, when the cell fate declines either to be αβ- or γδ-T cells [34] [36].

The exact relationship between tension-dependent error correction and checkpoint status is elusive (Khodjakov and Rieder, 2009; Nezi and Musacchio, 2009; Santaguida and Musacchio, 2009; Khodjakov and Pines, 2010; Lampson and Cheeseman, 2010; Maresca and Salmon, 2010).

We account for this discrepancy by possible bias caused by a great disparity in the number of γ-H2AX foci in a cell population, in the focal sizes and intensities, and by variations in the cells' proliferative status, as well as their checkpoint status and expression of p53 or other proteins involved in genomic stability that could have changed due to genetic drift over time.

Customised cisplatin treatment, based on a reduction in nucleotide excision repair function, is one attractive approach, whereas mitotic checkpoint gene status can be used to guide docetaxel therapy.

mTORC1 signalling serves as a 'growth checkpoint' surveying the status of the extra- and intracellular milieu of growth factors and nutrients 83, 96.

We propose that perhaps KRAS activation and LKB1 loss permit liberation from cell cycle and energy status checkpoints, respectively, which allow for a metabolic advantage.

Autophagy can also be induced in the ovary during two earlier nutrient status checkpoints in germarium and mid-oogenesis stages, both in nurse cells and follicle cells, somatic epithelium surrounding germ cells [ 126– 128].

As Congress heads toward floor debates on the effort to overhaul the nation's health care system, the Prescriptions blog introduces a new feature: Checkpoint, a frequently updated status report on the health care debate in Washington and beyond.

Besides the difference in species, there are two key differences that must be considered for these studies, namely, the presence of telomerase and the status of checkpoint pathways.

Breast cancers of the luminal subtype expressing low levels of Cdc7 undergo a cytostatic G1 arrest after Cdc7 inhibition due to their p53 wild-type status, a checkpoint response mimicking untransformed cells.