Sentence examples for checkpoint respectively from inspiring English sources

These results support our annotation of the modules to separate cell cycle processes and to denote them mitotic progression and mitotic checkpoint, respectively.

Therefore, we examined cyclin D1, E and A cdk2 activities in TM10 and TM2H cell cultures after 24 h treatment with SAHA because they reflect kinase activities before, during and after the G1 → S checkpoint, respectively.

BRCA1 S1387 and S1423 are targets of phosphorylation by ATM and these phosphorylations are required for the intra-S and G2/M checkpoints, respectively [ 46- 48](Table 1).

Phosphorylation and dephosphorylation of H2AX have been implicated in the activation and de-activation of DNA damage-inducible cell-cycle checkpoints, respectively.

We propose that perhaps KRAS activation and LKB1 loss permit liberation from cell cycle and energy status checkpoints, respectively, which allow for a metabolic advantage.

Unsynapsed autosomes and unpaired XY DNA at pachytene triggers DDR machinery accumulation to protect the cell from meiotic progression until synaptic completion or to escape checkpoint surveillance, respectively [ 44, 50].

CDC7 (cell-division cycle 7 homolog of S. cerevisiae) and BUB1 (budding uninhibited by benzimidazoles 1 homolog of S. cerevisiae) encode protein kinases which induce G1/S transition and are involved with the spindle checkpoint function, respectively during cell mitosis.

The results showed a higher fraction of TK6 cells in S phase 24 h after MNNG treatment, and a time-dependent increase in the fraction of cells in sub-G1, indicating induction of an S-phase checkpoint and apoptosis, respectively.

Anaphase is initiated in the presence of misaligned and lagging chromosomes, indicative of a weakened checkpoint and persistent merotelic attachments, respectively.

Therefore, the number of times each gene appeared in checkpoint modules and gatekeeper modules, respectively, was calculated and two sets of the 10% and 20% most frequently occurring genes were selected as representative genes.

For example, pathway 35 and 73 are annotated as the pathways involved in mitotic spindle checkpoint and condensed chromosome kinetochore, respectively.