Sentence examples for checkpoint model from inspiring English sources

Both of these molecular genetic scenarios are consistent with the cell "death by checkpoint" model of BRCA function [22].

In both the competition model and the checkpoint model, kinetics plays a prominent role, but in the latter case, the cell has developed additional safeguard mechanisms.

Recently, it was found that the regions of the cell with the highest concentrations of newly delivered exocytic proteins (some of which are undoubtedly endocytic cargo) colocalize with the most rapidly maturing early coat patches (Layton et al. 2011), consistent with the checkpoint model.

Checkpoint models propose that Mad1 and Bub1 act as stable kinetochore-bound scaffolds, to enhance recruitment of Mad2 and Mad3/BubR1, but this remains untested for Bub1.

It is now time to integrate these Mad3/BubR1 findings with the checkpoint models that have been generated from structural studies of Mad2, Mad1 and Cdc20 [25], [25].

More recently, Mistry and collaborators elaborated a modification of the model proposed by Sear and Howard (Mistry et al, 2008) that presents the first attempt to describe the dynamics of microtubule attachment to the kinetochores, an important step in making spindle assembly checkpoint models closer to biological reality.

Nearly two decades ago, Wakeland and colleagues proposed a three-checkpoint model for the development of SLE based on their studies dissecting lupus genetic susceptibility using congenic mouse strains [ 5].

We propose LXCloud-CR our new decentralized Checkpoint-Restart model based on a distributed checkpoints repository using key–value store on a Distributed Hash Table (DHT).

But because of concerns about theft, the New York Public Library's Mid-Manhattan branch, which has two Checkpoint RapidCirc models, still encloses many audio and video items in security cases that must be removed by library staff members.

The mass-action G1/S and G2/M-DNA damage models described only the molecular logic in their respective checkpoints; the G1/S model was composed of 16 dynamic protein balances, 2 species constraints and 44 parameters while the G2/M-DNA damage model consisted of 15 dynamic protein balances,1 constraint and 40 parameters.

Note that no property is derived from the G1 phase checkpoint because Boolean models based on the Li, et al.'s study do not completely include genes related to the checkpoint.