Sentence examples for checkpoint is consistent from inspiring English sources

The existence of an invasion checkpoint is consistent with previous observations with the neural crest and with the concept of epithelial plasticity, where an incomplete EMT is observed (Barembaum et al., 2000; Thiery et al., 2009).

These results together with the normal function of CHEK2 in DNA damage checkpoints are consistent with the idea that CHEK2 might act as a tumour suppressor gene.

By down-regulating Bub3 using RNAi, we showed that depletion of Bub3 abrogates the metaphase arrest induced by nocodazole, further indicating that Bub3 functions as a checkpoint protein, which is consistent with previous studies [30], [62], [63].

This suggests that Ark1 has important Mad/Bub checkpoint substrates, which is consistent with our previously published budding yeast work [6].

Moreover, spontaneous checkpoint recovery without completion of DNA repair is consistent with the checkpoint adaptation phenomenon characterized in yeast, Xenopus, and mammalian cells [ 25, 26].

Stochastic analysis then showed that the direct spatial regulation can allow temporal positive feedback to enhance the robustness of the cell size checkpoint in fission yeast, which is consistent with the experimental data.

This is consistent with a checkpoint when additional EMT stimulatory and inhibitory signals are received to regulate invasion.

Upregulation of invasion markers (including proteases, ECM molecules and Zeb2) by OLFM1 is consistent with a checkpoint to regulate the final cell invasion.

The tel1 Δ SC interactions with PCNA-like checkpoint genes are consistent with a previous study (Guenole et al. 2013) To test if the SC interactions were specific to DNA damage or were common to other stresses, we tested the fitness of the double mutants in the presence of cycloheximide (CHX), which inhibits protein synthesis.

This is consistent with BRCA1 regulating checkpoints and cell proliferation.

This is consistent with a transient checkpoint-mediated cell-cycle arrest followed by recovery of proliferative capacity.