Sentence examples for checkpoint in response from inspiring English sources

The Houthis murdered a top Saleh aide at a checkpoint; in response, to prove his popularity, Saleh threw a huge celebration in Sana'a, with giant banners and blaring music.

The Nbs1 protein, hypomorphic mutant in Nijmegen breakage syndrome (NBS), is a component of the Mre11/Rad50/Nbs1 (M/R/N) complex that acts as a DNA double-strand break sensor and functions in cell cycle checkpoint in response to DNA damage and DNA repair.

We sought to identify proteins that could modify the G1/S checkpoint in response to yca1 by using comparative proteomics.

One likely candidate is p38 MAPK, which can contribute to the G1-S checkpoint in response to diverse stimuli in a p53-independent manner.

It has been reported that the C-terminal region of Chk1 may activate the checkpoint in response to distinct DNA damage lesions [28], [31].

To test if activation of DNA damage checkpoint is required for UV-induced Rpb1 sumoylation, we examined the modification in cells lacking Mec1, which plays a key role in activation of checkpoint in response to UV DNA damage [2].

The Malovan-based battalion set up its first roadblock on 26 March, and the Kupres Battalion established its own checkpoints in response the following day.

Aphidicolin can cause a change in cell cycle progression either directly through the inhibition of DNA polymerases or indirectly through activation of checkpoints in response to induced DNA damage.

Thus it is conceivable that human HSCs experience telomere shortening and the induction of checkpoints in response to telomere dysfunction could contribute to the decline in stem function during aging.

Moreover, MAPKAP kinase-2, a direct downstream target of p38 SAPK, is directly responsible for phosphorylating Cdc25B and C and for maintaining the G1, S, and G2/M checkpoints in response to UV-induced DNA damage [37].

Likewise the activation of cell cycle checkpoints in response to DNA damage was intact under these latter conditions as was evidenced by S-phase cell cycle arrest following the induction of double strand breaks.