Sentence examples for checkpoint in determining from inspiring English sources

Finally, Gi-mediated inhibition constitutes an important checkpoint in determining nociceptor excitability.

In metazoans, a transient increase in the ΔΨm is thought to serve as a key checkpoint in determining cell fate, and is correlated with increased production and accumulation of reactive oxygen species (ROS) by the mitochondria during apoptosis.

Law enforcement officials say demographics play no role in determining where the police establish checkpoints.

The experimental data indicate that the cell cycle arrest occurs at different phases for the two V species analyzed (G2 checkpoint for VN and G0/G1 for VS2), showing the importance of the chemical form in determining their mechanism of action.

These results suggest a cooperative role for wtp53 and RAF1 protein in determining cellular radiosensitivity in human cells, which involves control of the G2/M checkpoint.

CHK1 has for long been known as a key player in determining cellular responses to DNA damage and governing G1/S, S, and G2/M phase checkpoints [ 48].

We demonstrate several quality control checkpoints at the library preparation, pre-sequencing, post-sequencing, and post-alignment stages, which should prove useful in determining sample and processing quality.

Thus there are two key factors in determining the extent of perturbation on the cooperation network: (1) the number of gene hits in gatekeeper modules and (2) the number of active links between gatekeeper modules and checkpoint modules (meaning simultaneous hits on gatekeeper modules and their linked checkpoint modules).

The regulation of the mitochondria intrinsic pathway is performed by a complex protein network in which the B-cell lymphoma protein-2 (Bcl-2) family members form a central checkpoint that determines whether a cell lives or dies [20].

In accord with these results, the knockdown of lincRNA-p21 had no effect on the cell cycle distribution and the DNA damage checkpoint as determined by FACS analysis.

Thus, oxidation and mitochondrial transport of cofilin represent checkpoints that determine T-cell fate in oxidative stress conditions.