Sentence examples for checkpoint conditions from inspiring English sources
It violates the property 4 of the M-metaphase checkpoint conditions (see Additional file 1).
The cell cycle can proceed to the next phase properly only if checkpoint conditions are met.
The proposed model is the timing-robust model that properly preserves all the essential checkpoint conditions against timing variations.
We derived the logical properties to check from essential checkpoint conditions of the budding yeast cell cycle.
In this study, we present a timing-robust model that properly preserves all the essential checkpoint conditions against timing variations.
Only recently, some studies suggested extension of such models towards timing-robust models, but they have not considered checkpoint conditions.
Each checkpoint condition is translated into a group of specific sequences of state transitions that can be derived by ordering pairs of state transition among Clb2, Cdc20 and their interacting genes.
In particular, such models violate the M phase checkpoint condition so that it allows a division of a budding yeast cell into two before the completion of its full DNA replication and synthesis.
Here, we report an analysis of the role of Aurora B in the spindle checkpoint under conditions believed to uncouple the effects of Aurora B inhibition on the checkpoint from those on error correction.
When treated with neocarzinostatin (NCS, radio-mimetic chemical, 1 μg/ml), accumulation in G2/M-phases was observed in control U2OS cells (59.3 ± 5.9%), however this NCS-induced G2/M-arrest was abrogated in U2OS Sh2 and Sh16 cells (33.27 ± 0.5 and 42.9 ± 2.2% respectively), indicating that BRAT1 is involved in G2/M checkpoint under conditions of DNA damage as shown in our previous report [ 1].
Expression of BubR1B1 loop did not overtly affect the kinetochore levels of endogenous Bub1, suggesting that the multiple MELTP sequences of Knl1 are not saturated with endogenous Bub1 even in the strong checkpoint-activating conditions of our assay.
