Sentence examples for checkpoint complex from inspiring English sources

The mitotic checkpoint complex (MCC) coordinates proper chromosome biorientation on the spindle with ubiquitination activities of CDC20-activated anaphase-promoting complex/cyclosome (APC/CCDC20).

The mitotic checkpoint complex (MCC) ensures the fidelity of chromosomal segregation, by delaying the onset of anaphase until all sister chromatids have been properly attached to the mitotic spindle.

This acceleration correlates with absence of detectable mitotic checkpoint complex after Mps1 inhibition.

Thus, this fact suggested that the spindle checkpoint complex may also participate in a function in collaboration with histone modification.

Tof1 is a subunit of the Tof1-Mrc1-Csm3 checkpoint complex, which acts at the stalled replication fork [34] [36].

The mitotic checkpoint functions through the production of an inhibitory complex called the mitotic checkpoint complex (MCC).

However, the VID21 gene was found to be grouped with prefoldin complex, which had synthetic lethal interaction with spindle checkpoint complex except BMH1.

Upon Ark1 inhibition, checkpoint complexes are disassembled and cyclin B is rapidly degraded.

We propose that TRIP13 and p31(comet) collaborate to inactivate the spindle assembly checkpoint through MAD2 conformational conversion and disassembly of mitotic checkpoint complexes.

These immunoprecipitations were carried out under non-saturating conditions of the Cdc20 antibody, resulting in the isolation of mostly mitotic checkpoint complexes (MCCs) bound to the APC/C in mitosis.

An intriguing possibility is that the asRNA provides a checkpoint in complex I assembly, down-regulating the expression of N-module-encoding genes until the rest of the complex has been synthesized/assembled.