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The results suggest that TAPBPR acts as a quality control checkpoint, closely monitoring and ensuring that the loaded peptide is stable within the MHC class I molecule.
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The principal reform was the establishment of a new timeline for the provision of rehabilitation services under the sickness absence program with checkpoints closely aligned with assessment of work capacity and a reduction of the cash value of sickness benefits for those who did not return to work.
But when they reached the border they realized that their situation was perilous: the checkpoint was closely monitored by armed guards.
Progression of the cell cycle past these checkpoints is closely monitored and regulated by a cell cycle control system [ 66].
The DNA damage response and cell cycle checkpoints are closely linked, and there is substantial overlap of signaling factors in both processes.
The scene, she wrote, more closely resembled "checkpoints than picket lines".
(To get into Chechnya, I had to disguise myself as a Chechen woman, wearing a scarf and long skirt, and pray that I wouldn't be questioned closely at checkpoints).
People lining up to go through a checkpoint are being observed more closely — by security agents with psychological training, to help spot people whose behavior suggests they are up to no good.
The transcriptional regulation of cell cycle regulated genes may be closely related to checkpoint functions upon DNA damage.
This suggests that the pool of Aurora B responsible for the checkpoint response might reside very closely to its substrates.
Both pch-2 and sir-2 have been closely associated for checkpoint functions and protection of repetitive DNA (rDNA) in yeast [ 23].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com