We therefore compared the phases of the robust circadian transcriptome (FDR <0.05) in multiple tissues in [ 33] against the analyzed ChIP-seq data for E-box activators, D-box repressor and RRE regulators in order to check for characteristic patterns of phase regulation by these TFs.
Because both classes of ncRNA possess secondary structure motifs, in silico folding of sequences is subsequently performed to check for characteristic structural motifs as means to ascertain functionality using covariance models (snoRNAs, see [ Nawrocki et al. 2009] or stem-loop folding miRNAs, [ Hofacker et al. 1994]), respectively.
We checked for a characteristic motif present within each cluster which might provide a clue towards the target binding specificity of these clusters.
Potential confounding and effect-modification is checked for sociodemographic characteristics, number and type of chronic disease, (I ADL functioning (GARS), cognitive decline (IQCODE), mood (CES-D), behavioral problems (incontinence, sleep, agitation en aggression), medication use (centralized pharmacy data base) (Table 4) [ 28- 30].
The mortar is first checked for the two characteristics of printability (extrudability and buildability) by a manual home-made device.
Most of the ST sequences obtained in the above searches, checked for chickpea ST characteristics as explained below, are summarized in Additional file 1.
Two independent double mutants were used to check for the characteristic stomatal guard cell staining pattern after staining with Sytox Green (Invitrogen, CA) – both yielded identical results.
The purity of the SW1222 cell line was verified by routinely checking for its characteristic glandular morphology, when established in vivo (Richman and Bodmer, 1988) and by performing PCR-based microsatellite genotyping analysis [Health Protection Agency (HPA), UK].
The collected data will be checked for completeness and the characteristics and frequency of missing data will be described.
Several statistical tests can be performed to check for these characteristics, but they often imply that the distribution of the observations is not significantly different from a normal distribution, a characteristic that our data do not possess, as shown in Figure 1.
