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To check these models, we compared these models MSE in both previous and recent simulation studies.
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A promising new approach to ensuring MOD quality is generating metabolic models directly from an MOD, and then checking these models for correctness against experimental data sets.
To confirm the robustness of each model, leave-N-out cross validation (LNO) was carried out and the y-randomization test was used to check if these models present chance correlation.
The aim is to check whether these models are able to provide accurate solutions of residual stresses for three aerospace grade aluminium alloys of medium thickness so that fatigue life can be estimated using these residual stress models without going to the formidable finite element analysis.
Further details about this comparison are provided in Additional file 1: Appendix 5. To check how well these models fit the lung cancer data, we report in Table 4 a comparison of profile regression with CART [ 8] using logistic-type residuals [ 11].
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Similar bias can also be observed in Takano et al. The visual predictive check provided evidence that these models adequately capture the central tendencies and distribution characteristics of the observed data.
To check the validity of these models, we searched for significantly downregulated genes within the KEGG term Wnt signalling pathway in a previously published exon-level analysis of the androgen-responsive LNCaP transcriptome [26].
As a robustness check, the model was re-estimated subject to these constraints.
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