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We used an automated procedure to check annotation records of individual observer for errors or potential problems.
In future, the curator plans to automate all annotation pipelines so that once a newly reported β-lactamase gene passes the initial quality check, annotation can be done automatically.
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CSO validator reduces time spent on checking annotation mistakes and correcting problematic parts.
How our tool finds obvious modeling errors by checking annotation mistakes was described in the paper (Jeong et al., 2011).
The re-annotation procedure could be used directly, or after the adaption of detailed methods, for checking annotations of any other bacterial or archaeal genomes.
We analysed the functions of all regulated genes by domain searching, and checked annotations manually with reference to the literature (see Methods and Additional files 2, 3 and 4. With some notable exceptions, most clusters contained genes with a variety of functions.
Therefore, we decided to check the annotation file reporter by reporter.
Researchers can check gene annotation and submit information to the GENOME MAP group.
In addition, evidence types are also used by GO as a quality control check for annotation consistency.
A module to check manual annotation, called the inspector, was integrated in the implementation of Chado, with database triggers that calls SQL functions for monitored events.
It also provides an information system for researchers to check gene annotation and submit information to the SSB genome-sequencing group ([email protected]).
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