Your English writing platform
Discover LudwigExact(1)
In the context of metabolic engineering, the source set is composed of all naturally produced chassis compounds (endogenuous chassis metabolites) and the target set can be any compound of the chemical space.
Similar(59)
By systematically manipulating Parts and Devices within an appropriate Chassis, the resulting compounds can be assembled in a library for drug discovery.
More precisely the user enters a target compound, a chassis organism, and our software tools return a ranked list of pathways (each list being composed of enzymes) to be engineered into the chassis organism.
Based on the abovementioned two chassis strains, producers of further aromatic compounds were constructed.
Compound toxicity in the chassis organism E. coli was estimated through a partial least squares structure-activity relationship model implemented from an in-house database for E. coli of 150 compounds with experimentally determined IC50 (half maximal inhibitory concentration).
First, multiple catabolic routes for the degradation of aromatics and related compounds were inactivated, thereby obtaining the chassis strain P. taiwanensis VLB120Δ5 incapable of growing on 4-hydroxybenzoate (ΔpobA), tyrosine (Δhpd), and quinate (ΔquiC, ΔquiC1, ΔquiC2).
We consider the possibility of engineering metabolic pathways in a chassis organism in order to synthesize novel target compounds that are heterologous to the chassis.
An alternative protein delivery method involves intracellular production of the active compound and subsequent lysis of the bacterial chassis.
Therefore, P. pastoris is well suited as a chassis cellular system to convert methanol to various value-added compounds (Schwarzhans et al. 2017).
Pirelli would later diagnose the problems with the tyre compounds as originating from developing them on a testing chassis that was two years out-of-date at the time.
This soil microbe has been studied extensively as an model organism for biodegradation of aromatic compounds and it has been highlighted as an optimal chassis for implantation of synthetic genetic circuits.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com