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Given it is currently unclear how this gene fits into the pharmacodynamic and/or the pharmacokinetic pathway of the drug, an exciting avenue for future research is confirming the role of this gene in human MTX toxicity and characterizing its role in the pathway.
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While the role of Nb in forming precipitates has been well characterized, its role in a solid solution is less well understood due to the difficulty of obtaining quantitative experimental data.
We therefore decided to choose one of the identified negative regulators in our screen to further characterize its role in IL-1β secretion.
Here, we have performed an extensive mutational analysis of the HCF-1 Basic region and characterized its role in G1-phase progression and association with the Sin3 HDAC.
Further work on this protein will be required to further characterize its role and to elucidate its role in virulence.
Vitamin D has since been studied in several clinical trials to characterize its role in respiratory infections.
The timing and pattern of spib expression prompted us to characterize its role during primitive myelopoiesis in Xenopus tropicalis.
Therefore, we tired to clone an ABF gene from trifoliate orange, and functionally characterize its role in dehydration/drought tolerance.
Although the role of WASP in lymphocytes and myeloid cells is well characterized, its role on megakaryocyte (MK) development is poorly understood.
We developed a novel gene set based on this network's topology and applied the GSAS metric to characterize its role in patient survival.
Flotillin was shown to co-localize with Cry4Ba toxin in Aedes aegypti larval gut brush border membranes [ 25], and further investigation of its Cry-binding ability will contribute to characterize its role in Bti toxin resistance.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com