The third population, a bivariate normal distribution with the center below the y = x line, characterizes down-regulated genes.
To further characterize down-stream target(s) of Rac1 in cell migration, we investigated the role of IQGAP1, a IQ domain protein with a region containing sequence that has homology to RasGAP [41], in [S1P]ext mediated wound healing.
(Incidentally Callas characterizes locking down email from prying eyes as a "five to twenty years problem".
The mechanisms of deep-focus earthquakes at depths of 400 500 km beneath the Izu Bonin arc, including the detected earthquake sequence, are characterized by down-dip compression (e.g., Alpert et al. 2010).
Soligo responses to prolonged drought were characterized by down-regulated " transporter".
N deficiency was characterized by down-regulation of transcripts involved in phosphate transport, oligosaccharide biosynthesis and amine metabolism (Table 5).
Tumors developed from 4w-4 MIN-Os were characterized by down-regulation of immunoglobulin and up-regulation of actin and myosin (3- to 4-fold change).
The second set of miRNA (potentially activating Wnt/β-catenin signaling) is characterized by down-regulation in mature adipocytes and up-regulation in lithium-treated pre-adipocytes and adipocytes in the Li+MDI group.
Our data demonstrate that the adaptive changes in the proteome of tamoxifen resistant breast cancer cells are characterized by down-regulated ER signaling, activation of alternative survival pathways, and enhanced cell motility through regulation of the actin cytoskeleton dynamics.
Cytotrophoblast progression through the cell column and differentiation into the invasive phenotype is normally characterized by down-regulation of the integrin α6β4, which may be a receptor of LN (Damsky et al., 1992; Aplin, 1997).
The ecodormancy/budbreak transition (MAR to APR) was characterized by down-regulation of specific functional categories involved in starch and sugar catabolism or signaling and stress responses mainly related to previous periods.
