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In Toxoplasma gondii, Mullapudi et al. (2009) identified putative cis-regulatory elements present upstream of functionally related groups of genes and subsequently characterized the function of some of these conserved elements using reporter assays in the parasite [ 18].
In this study, we characterized the function of the A. cellulolyticus gene, creA.
When we characterized the function of the 34 prostate genes, we found they were significantly associated with BCR free survival (Figure 6) and to multiple cancer pathway genes (Figure 7).
However, although this reductionist approach has successfully characterized the function of a significant number of genes, the translation of these research outcomes into the field is scarce (Nelissen et al. 2014; Groen and Purugganan 2016; Gilliham et al. 2017) and the release of improved varieties is even rarer.
We further characterized the function of miRNAs differentially expressed under two conditions and found that ESCs exhibited higher degree of dependency on miRNAs for rapid proliferation; since Dgcr8−/− or Dicer1−/− but not wild-type ESCs showed slower growth rate and more accumulation in the G1 phase under 2i than serum condition.
This study isolated a mas (More Axillary Shoots) mutant, which was identified as an allele of the mitochondrial AAA-protease AtFtSH4, and characterized the function of the FtSH4 gene in regulating plant development by mediating the peroxidase-dependent interplay between hydrogen peroxide (H2O2) and auxin homeostasis.
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Previously, we have genetically and molecularly characterized the functions of PCFS4 in flowering time control.
Our lab has characterized the functions of human mitochondrial protein peptide deformylase (HsPDF).
Here, we characterized the functions of these potential HIF‐1 regulatory genes in lifespan regulation.
While a few subunits have been partially characterized, the functions of most complex I subunits are still unknown.
To investigate the mechanistic role of PK in epilepsy, the authors characterized the functions of wild-type and epilepsy-related mutants in a zebrafish model.
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