was first reported by Davis [ 6], and further characterized by Sun et al. [ 7].
Xeroderma pigmentosum (XP) is a rare, inherited disorder of DNA repair characterized by sun sensitivity of exposed tissues (skin, eye, oral mucous membranes) and a greater than 10,000-fold increased risk of cutaneous, ocular, and tongue neoplasms [ 1- 4].
MCF7/Aro, MCF7 3(1), T47D/Aro and T47D, human breast carcinoma cells stably transfected with the aromatase or empty control expression vectors, respectively, carrying the neomycin (G418) resistance gene, were generated and characterized by Sun and coworkers [ 34].
The participants were divided into two groups according to their sun exposure history: 157 women were characterized as sun-seeking, and the other 141 were classified as sun-phobic.
These maize genes are homologous to recently characterized plant SUN-domain protein genes from Arabidopsis (AtSUN1, AtSUN2 [ 54, 55]) and rice (OsSad1 [ 18]).
Another solar characteristic, sunspots, is patches on the surface of the sun characterized by locally diminished brightness and temperature and corresponds to the changing magnetic field within the sun [ 11].
Out-of-field stray light was characterized using the Sun as a stray light source.
Sigmar also shares a high amino acid identity (39%) and similarity (62%) with TIPE2, the other characterized TNFAIP8 family member (Sun et al., 2008).
It is characterized by an extreme sun sensitivity especially to Ultra Violet Radiation (UVR) that induces cutaneous and mucous membranes cancers of the eyes and mouth [ 1].
Bloom syndrome is an autosomal recessive disorder, characterized by "short stature, sun-sensitive skin changes, an increased risk of cancer, and other health problems".
