To test whether the upstream leader region of fhlA facilitates the interaction with OxyS and Hfq as previously described for the rpoS-DsrA system [23], the leader sequence of fhlA was extended from the previously characterized position −53 relative to the start codon, to −136 and −220 respectively.
He will begin trying to build enthusiasm among some of the voters who propelled him to victory in 2008, like college students, while Democratic strategists are considering ways to turn the increased prominence of the Tea Party movement to their advantage by characterizing positions taken by some Tea Party-backed Republican candidates as extreme.
Yuan et al. [5] employed a Hidden Markov Model (HMM) to characterize positioned or delocalized nucleosomes.
Note that the information content varies between 0 and 4.2 bits and signifies the overall sequence conservation for a particular cluster, while the sequence logo characterizes position specific residue conservation.
To gain a better understanding of the sequence patterns that characterize positioned nucleosomes, we first performed an analysis of the periodicities of the 256 tetranucleotides in a yeast genome-wide library of nucleosomal DNA sequences that was prepared by in vitro reconstitution.
In contrast to simple sequence motifs of fixed length, i.e. position specific scoring matrices, pHMMs are suited for identifying motifs that are interrupted by segments of variable length, and are used to characterize position-specific sequence similarities within a family of proteins.
We also characterized nucleosome positions on the leading and lagging strands, uncovering differences in chromatin maturation dynamics at hundreds of genes.
The tumor suppressor genes were selected because both p16 and p53 have well characterized CpG positions in their promoter regions.
We have characterized nucleotide positions in Asian ape TNF promoters that underlie functional changes in cell type- and stimulus-specific activation of the TNF gene.
To further test the hypothesis that neocentromeres can form at both active and inactive chromosomal loci, we characterized the positions of neocentromeres on chromosome 5.
The sub-sequence made up of the stretch of bases between the CRE and the TSS was characterized at positions 45 through 88.
