We have produced and extensively characterized overlapping regions of human members of the FXR family spanning the conserved N-terminus.
The 1H-NMR spectra of BD blood serum samples are characterized by overlaps that resulted in broad and intense peaks.
The advent of next-generation sequencing (NGS), which analysed all known disease-associated genes in parallel in a cost- and time-effective manner, eased this process of disease definition and also for vascular anomalies that are a heterogeneous group of vascular tumors and congenital circulatory malformations and often characterized by overlapping phenotypes.
The spectral region 1,400 to 1,200 сm−1 is characterized by overlapping deformation vibrations of the C-H bond in methyl and methylene groups of peptide fragment, stretching vibrations of the С-О bond in carbonyl group and amide III vibrations (stretching vibrations of С-N bond and N-H bend in plane) and the Si-O-Si, Si-O and O-Si-O vibration bands of the silica matrix.
The third observation suggests a likely evolutionary scenario, in which the SAP family of proteins originated by duplication-divergence of an individual PDZ domain within an ancestor protein, followed by duplication-divergence of a whole protein to generate the family members characterized by overlapping but distinct biological roles/functions [11], [12].
Hematopoietic ontogeny is characterized by overlapping waves of primitive, fetal definitive, and adult definitive erythroid lineages.
A large number of studies proved that mutations of functionally related genes are associated with genetic diseases characterized with overlapping phenotypes [ 1, 2].
Therefore, the differences in genetic load driven by the age of onset quantitative trait loci suggest that the two groups (high P-Hat and misclassified) are characterized by overlapping but distinct genetic profiles.
Since integrated care delivery is characterized by overlapping care processes performed by multiple professionals, the complementary role of each health care professional and the interdependency among them are important features [ 23, 24].
Autoimmune bullous diseases (ABDs) represent a group of rare, acquired disorders characterized by overlapping features with involvement of the skin and mucous membranes, resistance to treatment, and potential lethality that comprise pemphigus, bullous pemphigoid (BP), epidermolysis bullosa, dermatitis herpetiformis, and linear immunoglobulin A bullous dermatosis.
Autoimmune bullous diseases (ABDs) represent a group of rare, acquired disorders characterized by overlapping features, resistance to treatment, and potential lethality. 1 The most important pathophysiologic mechanisms in the skin of these patients have been identified as disruption of the host immune system, which leads to clinical blister formation.
