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The Y strain of T. cruzi was used in all experiments except for the metacyclogenesis assay, in which the Dm28c strain is the best characterized model for in vitro differentiation [18].
This cell line provides a unique and well characterized model for the study of gut epithelial differentiation since these cells undergo functional and morphological differentiation to an enterocyte phenotype with microvilli, dome formation, and expression of sucrase-isomaltase several days after reaching confluence [20] [22].
The best characterized model for intron loss in multicellular eukaryotes is via homologous recombination between intron containing genes and spliced cDNAs produced by reverse transcription [ 42, 62, 63].
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It is also one of the best characterized models for biochemical, molecular and genetics studies among the Lophotrochozoa.
It is especially so for the chicken Gallus gallus and tammar wallaby Macropus eugenii, the most characterized models for avian and marsupial species, respectively.
The mouse retina is one of the best characterized models for in vivo vessel formation as it displays all of the morphological hallmarks of angiogenesis (i.e. sprouting, branching, fusion, remodelling and maturation) after birth (Fruttiger, 2002, 2007).
In vitro differentiation of 3T3-L1 mouse preadipocytes, one of the best characterized models for studying adipogenesis (Green and Kehinde, 1975; Kita et al., 2009), is accompanied by a remarkable increase in the expression of numerous mitochondrial proteins (Newton et al., 2011).
Using a well characterized model system for breast cancer, we define here the molecular and cellular consequences of adriamycin treatment in breast tumor cells.
The publications listed below show a variety of quantification and propagation approaches for characterizing model uncertainty.
We introduce LLARRMA as an approach for characterizing model uncertainty when working within the frequentist paradigm.
APC Min/+ mice are a well-characterized model for FAP, a genetic condition characterized by the formation of up to thousands of adenomatous polyps in humans (Su et al., 1992).
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