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Otherwise, indirect factors that remain to be characterized might contribute to the embryonic development of an unconditional stimulus-response loop.
Clearly, ATR, mitogen activated protein kinases, and CDKs and numerous IR-upregulated kinases not yet characterized might also regulate such a network, as in human cells [22], [37].
Although all RIFIN variants bear a motif for directing proteins onto the secretory route, out of the parasite and into the cytoplasm of the host cell, referred to as the Plasmodium Export Element PEXELL) or Vacuolar Transport Signal [ 24, 42], additional factors not yet characterized might enhance or interfere with protein export.
This suggests that splicing signals other than the ESE hexamers, which were originally defined for short exons [ 21], or the ESE octamers [ 23, 24] analyzed here, might exist in exon sequences, particularly, those that flank long introns; such signals that remain to be specifically characterized, might comprise a new class of ESEs.
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Cord blood (CB) natural killer (NK) and lymphokine-activated killer (LAK) cytotoxic cells are poorly characterized but might be used to treat minimal residual and/or recurrent malignant disease.
Other yet-to-be characterized regulators might also influence gene transcription in the FCT-region of Alab49.
The reversible behavior characterized above might then serve as a baseline to study more subtle effects (e.g. time-dependent and/or irreversible processes) that can be observed after many cycles or different strain rates.
Traditional folk remedies have not been well characterized and might include alteration of gut permeability.
Tables 1 and 2 describe biomarkers that have been characterized and might be potentially useful for clinical applications.
Once the biological material is characterized, this might aggregate additional data and thus extend our capacity to understand the molecular bases of adaptation.
It doesn't seem coincidental that a society that countenances jamming tubes up defenseless detainees' rectums a practice that might be reasonably characterized as "rape"—might also countenance, say, a massive stop-and-frisk regime in New York City.
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