Mean and median lifespan and survival curves were primarily used to characterize lifespan.
In C. elegans, the eat-2 mutants represent a robust genetic model of DR (Lakowski & Hekimi, 1998) that are characterized by long lifespan and reduced fat storage (Lakowski & Hekimi, 1998; Brooks et al., 2009).
Indeed, both mouse models, which shared the same mixed genetic background, were characterized by short lifespan, reduced weight gain, severe megalencephaly and ventricular enlargement, increased cortical thickness, cortical lamination defects, hippocampal alterations, hypomyelination, and spontaneous epilepsy.
PMD (Pelizaeus Merzbacher disease), a CNS (central nervous system) disease characterized by shortened lifespan and severe neural dysfunction, is caused by mutations of the PLP1 (X-linked myelin proteolipid protein) gene.
Adult TBPH−/− mutant and pan-neuronal Gal4-specific ELAV>TBPH GOF flies were characterized by shortened lifespan, with TBPH−/− adults dying around day 7 and pan-neuronal Gal4-specific ELAV>TBPH flies dying around day 35, when compared with wild-type controls with an average lifespan of 80 days (23, 24) (data not shown).
The visual, cognitive, and linguistic factors affecting picture-naming performance are very well characterized across the lifespan (Berman et al. 1989; Cycowicz et al. 1997; D'Amico, Devescovi, and Bates 2001; Iyer et al. 2001) and across languages (Bates et al. 2003; Szekelky et al. 2003).
Furthermore, M1dG analysis in different cell types that are characterized by different lifespans may potentially reveal differences between smokers and nonsmokers and should be considered in future studies.
On standard medium without added hydrogen peroxide the PaCatB deletion and PaCatB over-expressing strains and the wild-type are characterized by similar lifespans.
Predicting the popularity of an item before its publication is particularly useful for web content characterized by a short lifespan.
They are characterized by an extended lifespan without impairments of vital functions like growth and fertility.
32 The discrete processes for CTC kinetics (count data) in the total body blood were characterized by a cell lifespan model.
