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The phenotype of the transferred CD4 T cells also was characterized in mice euthanized at day 7 after infection.
The pathogenesis of Francisella tularensis, the causative agent of tularemia, has been primarily characterized in mice.
Recently, cervical thymus was identified and characterized in mice [35], [36].
The tissue chamber model has been extensively characterized in mice [13], [14] and accurately mimics bacterial infections in vivo.
The T cell effector functions, which could not be measured in guinea pigs due to technical limitations, were characterized in mice by multi-parameter flow cytometry.
Subsequently, T cell responses induced by the different vaccines were characterized in mice immunized twice (days 0 and 21) with the MVA- and rVVL-H1-Ca and N1-Ca constructs.
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Humoral immune responses were characterized in mouse strains lacking either or both B7 molecules.
Psickle has not previously been characterized in mouse models of sickle disease.
Originally characterized in mouse embryonal carcinoma cells, Rex-1 or expression from its minimal promoter is a marker of pluripotency [24].
Of the 4/18 genes (LIF, CSPG4, EDIL3, and MATN4) not associated with skeletal anomalies, two have not been characterized in mouse models.
In this study, skeletal development was characterized in mouse embryo mutant limbs devoid of skeletal muscle.
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