Several proteins responsible for or associated with these cancer traits have been characterized, exemplified by cell division (telomerase [ 74], Cyp1B1 [ 41], survivin [ 4, 7, 64, 73]), resistance to apoptosis (survivin, ML-IAP, Bcl-2, Bcl-X L), and Mcl-1 [ 1, 34]), metastatic potential (Heparanase [ 71]), angiogenesis (survivin, Bcl-2, VEGFR [ 50]), and drug resistance [ 43, 44, 82].
A series of new amphiphilic, semi-crystalline polyamides based on hexamethylenediamine and long alkane carboxylic diacids has been synthesized and characterized, here exemplified by polyamide 6.24 (PA-6.24) and polyamide 6.34 (PA-6.34).
The adverse metabolic effects of glucocorticoids are well characterized and exemplified in patients with Cushing's syndrome (8).
The proposed procedure to identify deleted genes is illustrated in Figure 1 and its potential to structurally characterize hemizygous deletions is exemplified below with Citrus mutants as starting plant material.
This can help us make deliberate choices, especially in situations that are characterized by apparently conflicting interests, as exemplified in this instance by the relationships among PI Sara, postdoc William, and graduate student Terry.
Lying at the most basic level of physics, the laws of mechanics are characterized by certain symmetry properties, as exemplified in the aforementioned symmetry between action and reaction forces.
Glycan species were characterized by tandem mass spectrometry as exemplified for the fucosyl disaccharide Fuc-HexNAc which had a relative abundance of 10.6% (Table 2; Fig. 2).
At one extreme are the class IV IRES sequences, which enable ribosome to translate their messages independently of any cellular initiation factors, exemplified by the widely characterized cricket paralysis virus IRES (CrPV-IRES) (Wilson et al., 2000).
While glycolysis and the TCA cycle illustrate pathways characterized by sequences of catalytic reactions, mammalian carbonic anhydrases (CAs) exemplify a single protein family, all the members of which catalyze the interconversion of carbon dioxide and bicarbonate [ 5].
c In cancer cells gain-of-function of oncogenes and loss-of-function of tumor suppressor genes (such as MYC, HIF1α and TP53) results in altered metabolism, exemplified by the Warburg effect, characterized by high glucose consumption rates.
Late diagonal bands of activity along low- and high-frequency borders, or V-shaped 'caps' of symmetric activity on TC low-intensity domains characterized PSTH's final time-slices, as exemplified in the two rightmost top panels of Fig. 3B.
