Sentence examples similar to characterized efficacy from inspiring English sources

This work also suggests that additional studies of novel therapies involving larger sample sizes may be required to confidently characterize efficacy.

These data demonstrate that the PEL/SCID mouse is an important preclinical model to characterize efficacy and anti-tumor mechanisms of new therapeutic targets in vivo and will be useful in the design and testing of agents in viral lymphoproliferative diseases.

Additional studies to characterize efficacy in RA and to determine the optimal dose regimen appear warranted.

We aimed to characterize efficacy and side-effects of continuous infusions of pentobarbital (cIV-PTB) treating SRSE.

The objective of this exploratory analysis was to characterize efficacy and onset of action of a 3-month treatment period with risperidone long-acting injection (RLAI), adjunctive to an individual's treatment regimen, in subjects with symptomatic bipolar disorder who relapsed frequently and had significant symptoms of mania and/or depression.

Herein, we characterized the efficacy, toxicity and pharmacokinetic properties of NP docetaxel formulations that have differential drug loading but are otherwise identical.

Of the selective AKT inhibitors, perifosine, an oral AKT inhibitor, has been the most characterized, with efficacy shown mainly in solid tumors and multiple myeloma.

Because every rodent model of ICH has drawbacks that limit its clinical relevance, 3 we further characterized the efficacy of EC for ICH in the blood model, another common strategy to recapitulate ICH.

This hypothesis was further explored by analysis of data from a large placebo-controlled dose-ranging study in subjects with SAR that characterized the efficacy of five once-daily desloratadine regimens (2.5 to 20 mg/d) at the end of the 24-hour dosing interval.

Characterize efficacy and triglycerides over time following alitretinoin administration to assess the most appropriate dose; Evaluate factors affecting efficacy and triglycerides; and Simulate clinical trials to assess the clinical relevance of any findings and potential labeling implications.

1– 3, 5 The overall goals of the LDR analyses were to: Characterize efficacy and triglycerides over time following alitretinoin administration to assess the most appropriate dose; Evaluate factors affecting efficacy and triglycerides; and Simulate clinical trials to assess the clinical relevance of any findings and potential labeling implications.