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All sequences characterized clustered with HGyV1 sequences, exhibiting either 100% nucleotide identity or 1 point mutation (corresponding to a nonsynonymous substitution, ala →thr).
When we characterized clustered protein coding genes (in group of ≥3) with small RNAs, we identified 26 clusters, which ranged in size from a cluster of 3 genes to clusters as large as 14 genes (Additional file 2: Table S2).
In particular, the PB1 gene of 16 of the 18 viruses we characterized clustered as described for the other 7 genome segments, whereas phylogeny of A/chicken/Bangladesh/12VIR-7140-7/2012 and A/chicken/Bangladesh/12VIrevealed6/2012 revealed that their PB1 gene derived from H9N2 subtype viruses.
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Free fatty acid receptor 1 (FFAR1) is a member of a previously characterized cluster of orphan G protein-coupled receptors (GPCRs).
A well characterized cluster is one containing the paternally expressed IGF2 and maternally expressed H19 in chromosome 11p15.5.
For the 6,725 novel clusters, 2,089 can be assigned to such "virtual operons," including 1,247 that are next to characterized clusters, providing possible hints to their functions.
However, 13 (29%) were sampled during global outbreak week 05, representing the first identified (and most characterized cluster) of human influenza A/H1N1(2009) (H1N1pdm) infections in Nova Scotia (NS), Canada.
In an effort to understand the rules regulating global gene expression during oligodendrocyte progenitor differentiation, we designed a kinetic clustering algorithm to interrogate the oligodendrocyte transcriptome [25] and characterized clusters of co-regulated genes defining complex waves of gene expression.
Deletion of the previously characterized cluster of two C/EBP and a FOXO site (reporter construct dPRL-270/luc3 dPRL-270/luc3fereducedpression by ∼50% (Fig. 5), refluciferaseexpressionly reported cooperativity bytween FOXO1A and C/EBP [13].
Emphysema, lesion that characterized cluster 14, is commonly associated with hypersensitivity pneumonia also called "farmer's lung".
The "other deteriorations" that characterized cluster 8 grouped together different lesions that revealed issues in the slaughtering process.
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