Multiple types of porosity in carbonate aquifer resulted in flow behavior that is difficult to characterize, because the porosity and permeability vary throughout the aquifer.
Misfolded protein conformations can be notoriously difficult to characterize because the tools of structural biology are most suited to proteins which adopt only single conformations that are extensively populated.
The long-term effect is difficult to fully characterize, because the SSR is only a pre-deleterious allele and its impact on fitness will be only moderate unless the deleterious frame-shifted allele is extremely likely to appear and is associated with a strong impact on fitness.
Nevertheless, the interaction with the upper atmosphere is not well characterized because of the absence of regular and dedicated in situ measurements at high altitudes; thus, current descriptions of the thermosphere are based on semi empirical models.
Besides such sources of uncertainty in samples, many unassigned peaks should also be due to promiscuous activities of enzymes not yet characterized because of the lack of an appropriate description of the mechanisms of enzyme promiscuity.
The INC set was not further characterized because of the small sample size.
Despite these findings, the transmission cycle of F. tularensis is not well characterized because of the rare occurrence of natural outbreaks involving humans.
Relatively little is known about the functions of most lncRNAs; however, a few species have been characterized because of the significance of their functions.
Annual nitrous oxide (N2O) emissions from high-altitude alpine meadow grasslands have not been effectively characterized because of the scarcity of whole-year measurements.
This subgroup is characterized because 90% of the cases belonging to it present the typical histology of an MB; the patients are older than 3 years old (it can also occur in adults but never in children under 3 years); it has a good prognosis and rarely shows metastasis [ 11, 12].
