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The gene regulation of numerous cytokines (Transforming Growth Factor-β, Bone Morphogenetic Proteins, Insulin-like Growth Factor-1, Fibroblast Growth Factor-2) during distraction osteogenesis have been best characterized and will be discussed in this text.
Cell-mediated immune responses are currently being characterized and will be reported separately.
Unfortunately, the steroid profile of XYM in FCG mice has not yet been characterized and will require further experimentation.
The signal transduction pathways activated by these pattern recognition receptors are quite well characterized, and will not be discussed in this review.
The biology of the underlying mechanisms is becoming characterized and will thus allow development of mechanistically based in vitro assays that will be scientifically validated and thus acceptable to regulatory agencies.
Similar(55)
Many genomes and transcriptomes are currently characterized and more will follow in the future [ 1].
Similarly, Christian Daughton, chief of the Environmental Chemistry Branch at the EPA National Exposure Research Laboratory, says there are "other solutes that are also present at the same time, most of which may not even be characterized and which will also engage in oxidative reactions" in the presence of the catalyst.
Eventually, the new disease will be fully characterized and other patients will be found who also have it (The New Yorker article covers this angle nicely).
Both scanners will be extensively described and characterized, and their potential will be demonstrated with some key application results.
F2 generation animals from the six remaining transgenic founder lines are currently being characterized and future work will report on their properties in greater detail.
However, the precise mechanisms associated with the synergistic effects observed in the present studies were not fully characterized, and mechanistic studies will be required to identify the role of different cellular subsets in the generation of effective antitumor immunity.
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