Sentence examples for characterized activity from inspiring English sources

The selectivity of PTC124 for premature termination codons, its well characterized activity profile, oral bioavailability and pharmacological properties indicate that this drug may have broad clinical potential for the treatment of a large group of genetic disorders with limited or no therapeutic options.

We have isolated temperature-sensitive (TS) EcoRI endonuclease mutants (R56Q, G78D, P90S, V97I, R105K, M157I, C218Y, A235E, M255I, T261I and L263F) and characterized activity in vivo and in vitro.

The final goal of these studies is to leverage this newly characterized activity of V to develop more specific and effective therapeutics and prophylactics against plague.

The first characterized activity of TXNs was the reduction of 2-Cys peroxiredoxins (2-Cys PRXs) [2], a ubiquitous class of sulfur-dependent peroxidases.

As we show below, such small systems demonstrate well characterized activity reflecting a clear transition from sporadic to well synchronized network level activity.

CpG dinucleotides were preferentially methylated, as expected from the previously characterized activity of mammalian DNMT3.

We characterized activity-regulated expression of lysine demethylases and lysine methyltransferases in the hippocampus of adult male mice following pilocarpine-induced seizure.

During ALC formation, AT II cells engage simultaneously in fundamentally different, but not fully characterized activities.

The experimentally characterized activities and functions of the key Cas proteins are listed in Table 1.

Moreover, many recently characterized activities have no associated protein entries, see Figure  4.

The SAR Index (SARI) provides a function to characterize activity landscapes defined by sets of active molecules in a quantitative manner [3].