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To increase the understanding of how the XOS are metabolized it is of interest to map and characterize the enzymes responsible for XOS degradation in putative probiotic strains, and in this work we have characterized a first enzyme from the putative probiotic strain 92, from the species Weissella.
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At the same time, we characterized a second isoform of SUV420H1 (designated SUV420H1_i2) and compared the activity of all three SUV420H proteins with regard to localization and H4K20 methylation.
In the current study, we characterized a second SUV420H1 isoform, designated SUV420H1_i2, and found it has markedly different activity when compared to the originally described SUV420H1_i1 and SUV420H2 proteins.
Further studies characterized a second HIF α isoform as also being tightly regulated by oxygen tension.
Therefore, we have characterized a second vertebrate model for studying the role of telomerase and telomeres in aging research.
In the current study, we have identified and characterized a second chicken apolipoprotein that appears to be absent from mammals.
We also characterized a second insulin receptor family member, EmIR2, and demonstrated interaction of its ligand binding domain with human insulin in the yeast two-hybrid system.
Based on the pioneering work of Estabrook, both Capdevila and Falck found and characterized a third pathway, microsomal cytochrome P450 arachidonic acid metabolism [ 14, 15].
Our findings are therefore of particular interest, since we have characterized a second interaction between a BBS gene and a schizophrenia susceptibility gene, both of which appear to have roles in intracellular trafficking.
We have previously identified GABP alpha/beta as a critical regulator of the BRCA1 promoter acting through the RIBS element [ 16] and in this paper we have characterized a second GABP alpha/beta site within the UP element.
Which, if you think about it, is the perfect way to characterize a first crush.
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