The cyclin-dependent kinases (CDKs) have been characterized in complex with a variety of inhibitors, but the majority of structures solved are in the inactive form.
However, none of these inhibitors have yet been structurally characterized in complex with a GRK and thus their mechanisms of action are unknown.
Neuronal activities of this complex, characterized in an in vitro brainstem-spinal cord preparation of the neonatal rat, have been hypothesized to underlie respiratory rhythm generation.
It should be borne in mind that a BBN analysis such as this should serve to inform wider decision judgements about eruptive potential – because of inevitable limitations in characterizing a complex dynamic volcano system, precise numerical inferences should not be relied on as absolute operational decisions on their own.
Our study, even though it uncovers generic features of genotype-phenotype maps with demonstrated relevance for evolutionary adaptation and innovation in other biological systems [ 7, 23], is thus best viewed as a modest beginning in characterizing a complex metabolic genotype space.
The complexes of Zn II 2,2′-bipyridine diacetate with salen (LH2) and salophen (L′H2) have been characterized in which complex with L′H2 in DMSO has yielded a novel one-dimensional molecular architecture of micrometer length.
A new approach has been developed to characterize bifunctional catalysts in a complex matrix of hydrotreated vacuum gas oil using a batch reactor test.
The ore-bearing domain, in contrast, is characterized by a complex internal architecture, variations in whole-rock and mineral compositions, and the presence of numerous inclusions and xenoliths.
Ribonucleoprotein foci of repeated CUG, CCUG, CGG, CAG, AUUCU and UGGAA motifs present in different human tissues, cultured cells and several model organisms have been characterized in detail providing a complex picture of foci morphology, abundance and molecular composition and their detection method.
In a context characterized by a complex multitude of interest groups, the bureaucrats tend to deal with the best-organized groups as a way of reducing complexity.
