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Quantitative proteomics, which is based on Liquid Chromatography (LC) and Mass Spectrometry (MS) technologies and can systematically identify and quantify proteins at a proteome-wide scale, has emerged as a novel and powerful methodology to characterize functions of various cell types and tissues in humans (Deng et al., 2011a).
To further characterize functions of transcripts with homology to known proteins, we obtained the Gene Ontology (GO) terms [ 60] associated with both the best UniProt and PFAM hits as determined by E-score for each non-redundant transcript.
On the basis of homologous DNA sequence, gene knockout technology was developed and many scientists have tried to characterize functions of various proteins and DNA elements on the basis of gene knockouts.
This research was devoted to develop an endosperm genotype-based genetic approach to characterize functions of previously mapped seed dormancy QTL in regulating germination through the embryo, endosperm, or maternal tissues.
Comparative mapping contributes largely to solve issues in the evolution of individual species, differences and similarities between various species and to characterize functions of genomes by providing a detailed analysis of conservation among orthologous intervals in different species [ 14].
Using an alternative analysis strategy to more broadly characterize arsenic-associated expression modification, we used EVA software to graphically characterize functions of the top ranked 12,484 genes selected by ReliefF algorithm.
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This novel pathway of caspase-1 mediated cell death adds a novel twist to the characterized functions of caspase-1.
Recently characterized functions of bacterial protein glycosylation include adhesion, protection against proteases, antigenic variation, and evasion of immunity [5], [12], [33] [38].
In this study we characterized functions of a novel Hog1-regulated kinase, Hrk1, in C. neoformans by molecular and genetic analyses.
Transcriptional regulation by methylation of histones and non-histone proteins is one of the more characterized functions of PRMTs.
Characterized functions of those genes are shown together with the background of previous studies in H. jecorina and ascomycetes in general.
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