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Specifically, we briefly showed how our indexes C k),S k),R(k) could be able to characterize altered ongoing activity in an experimental model of chronic pain.
Taken together, these results strongly support the application of the leukocyte infiltration index to transcriptomic studies to appropriately characterize altered mRNA and/or miRNA expression from heterogeneous biological samples, thus allowing for more meaningful interpretation of microarray data with the aim of increasing our understanding of the fundamental mechanisms of disease pathogenesis.
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The two most characterized altered metabolic pathways are high rates of glycolysis and glutaminolysis, which are natural targets for cancer therapy.
The characterized altered structure of glycation on VN results in the loss of binding between RGD-binding integrins and their ligands.
A total of 657 unique genes (from 1,355 probes) from this list were represented on the BeadChip, and the methylation levels were compared to identify "biologically-prioritized" candidate genes with previously characterized altered expression by the CTD.
However, all CFC mutations which have been biochemically characterized alter protein function to some extent ([18], [26]; Rauen, unpublished data).
Characterizing altered PK in patients receiving RRT while on ECMO can be complex.
Several studies utilized genome-wide expression profiling in order to characterize the altered gene expression in the prostate reactive stroma, either on a large cohort of patients specimens or in a exogenously modified stroma (49– 51).
Ototoxicity that yet occurs in no more than 10% of patients is characterized by altered perception of speech but is not accompanied by alterations in audiography.
Schizophrenia is a major psychosis that is characterized by altered perception, thought processes, and behaviors.
Irritable bowel syndrome (IBS) is one of the most common gastrointestinal illnesses and is characterized by altered visceral perception.
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CEO of Professional Science Editing for Scientists @ prosciediting.com