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It is nonetheless possible to recast the characterization of variations of neuronal excitability upon astrocytic uptake as an optimization problem under an equality constraint resulting from the implicit characterization of the SNIC bifurcation.
However the characterization of variations associated to specific phenotypes is still at its beginning.
Despite the advantages of exome sequencing, a number of barriers exist including unpolished genome assemblies, partial genome annotation, incomplete or poor characterization of variations in strains, and incomplete inbreeding of strains.
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The use of gene expression profiling in both clinical and laboratory settings would be enhanced by better characterization of variation due to individual, environmental, and technical factors.
The QUICS method has been used successfully for diverse experimental studies including disease biomarker identification, drug mode of action, toxicology, aging and characterization of variation in complex mixtures such as milk and on a variety of sample matrices (e.g., biological fluids, tissue, milk) [17 22].
When modeling food webs, choices must be made regarding the level of complexity for the web, assignment of species to trophic guilds, selection of representative species for guilds, use of average diets, the characterization of variation among individuals or guild members within a web, and the spatial and temporal scales/dynamics of webs.
Strengths of the BPC3 include its size and the comprehensive characterization of variation around the IGF1, IGFBP1, and IGFBP3 loci.
Comprehensive characterization of variation in highly polymorphic MHC genes requires PCR primers amplifying all alleles.
However, no extensive characterization of variation across IGF1 in grey wolf, the wild progenitor of domestic dogs, was done.
Haplotypes have the potential for improved characterization of variation across the locus set (Clark, 2004; Schaid, 2004).
The 1000 Genomes Project was started in 2008 with the aim to deliver deep characterization of variation in the human genome.
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