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During characterization of the test method, the specificity, accuracy, and intermediate precision of the assay was investigated based on regulatory guidelines.
A complete dynamic characterization of the test fixture is shown to be unnecessary; the only measurements required are the frequency response functions at the points of attachment to the bearing components.
In this context, the recently increased number of reports on GPCR ligand-biased signaling has further spurred the efforts in the pharmaceutical industry toward broader biological characterization of the test compounds, for example employing high-content screening to analyze different GPCR ligand-induced signaling pathways.
A detailed characterization of the test set is provided in supplementary table S6, Supplementary Material online.
KRT and OI were involved in the initial characterization of the test on clinical samples.
The key to all aspects of the experiment is the accurate characterization of the test material in terms of fiber length, diameter, particulate content, and chemistry.
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Comprehensive characterizations of the test atmospheres were performed according to the respective guidelines and OECD guidance documents (ECHA 2012; Hussain et al. 2009).
Unexpected behaviors, observed during the test experiments, are analyzed and discussed, revealing previously unknown characterizations of the tested algorithms that neither a complexity analysis, nor a random experimentation protocol could have revealed beforehand.
In Table 1, the physical-chemical characterization of the various test compounds is specified.
In order to investigate the influence of temperature on the behavior of the compressive strength on the samples, a uniaxial compression test and crystallographic characterization of the material tested through the technique of X-ray diffraction (XRD) were performed.
Surface characterization of the two tested groups showed distinct topographical features on ATT and CaP: formation of the CaP on titanium substrate resulted in micrometric topography, while alkaline-treated titanium substrate demonstrated nanometric topography.
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