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Applications include conditional inactivation as well as functional characterization of target proteins.
Hung, G. et al. Characterization of target mRNA reduction through in situ RNA hybridization in multiple organ systems following systemic antisense treatment in animals.
We propose a new and computationally efficient data-worth analysis and quantification framework keyed to the characterization of target state variables in groundwater systems.
In order to extend the experimental portfolio, we developed target‐directed proteolysis (TDP), an in vivo method allowing structural and functional characterization of target proteins in living cells.
The article closes with a discussion of the use of mouse molecular genetics for the characterization of target genes as downstream effectors of transcription factors.
For in vivo localization of drugs in tissues and cells, receptor microautoradiography was specifically designed to preserve both tissue structure and deposition of noncovalently bound diffusible compounds and to enable microscopic viewing, quantitative analysis, and characterization of target sites.
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Ghisolfi-Nieto, L., Joseph, G., Puvion-Dutilleul, F., Amalric, F. & Bouvet, P. Nucleolin is a sequence-specific RNA-binding protein: characterization of targets on pre-ribosomal RNA.
The present results illustrate several ways in which the foregoing characterization of target-based screens may oversimplify both their pitfalls and advantages.
Availability of a large transcript database of the target species also highly favored the identification and characterization of targets.
Characterization of targeting the uro-epithelium of bladder and the kidney by the use of the uroplakin II or uromodulin promoters has been recently initiated as mentioned above.
Over the past 5 years, significant technological breakthroughs in imaging hardware and image processing algorithms have also been introduced, enabling specific radiotracer imaging for improved characterization of targeted cellular and functional processes in clinical routine.
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