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MRI allows characterization of lesions through evaluation of the fluid content's signal intensity.
Characterization of lesions - in terms of volumes and molecular cellular characteristics - potentially assists staging, which predicts how aggressive the lesion will be in causing future disease in the patient.
This enables the characterization of lesions as small as 4 5 mm.
Both signal intensity and ADCs are mainstays in the identification and characterization of lesions in DWI.
However, characterization of lesions into benign and malignant abdominal etiologies is often not possible from structural imaging techniques alone.
Its excellent soft tissue contrast helps in the detection and characterization of lesions in the uterine cavity or the myometrium.
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We have recently published a characterization of lesion volume, the innate immune response, and locomotor recovery in male and female NOD-scid mice in comparison with C57Bl/6 and BUB/BnJ mice [14], and report that NOD-scid mice do not exhibit differences in lesion characteristics and are within the range of strain variation for both macrophage and neutrophil responses.
It enables complex and multifaceted depiction of tumour phenotype, improved characterization of lesion pathology and more accurate assessment of therapeutic response.
For BC patients with disease relapse, a volumetric characterization of lesion burden was made [ 13], considering a metabolic tumor volume (MTV) with a threshold of 40% of the maximum signal intensity (MTV40).
Deciphering the antigen specificity of the blood and/or CSF expanded CD8+ T cells would definitely give further insight into the exact implication of these cells in MS. Besides giving more insight into the TCR repertoire dynamics in the periphery and in the CNS in MS, our results also enlarge the characterization of lesion-infiltrating T cells.
The use of contrast agents allows perfusion mapping of focal lesions, thus enabling characterization of focal lesions.
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