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Functional characterization of different isoforms of the CD44 family, however, is still limited.
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Additional research, including targeted analysis of different isoforms of lipid biosynthetic enzymes, and global, proteome-wide characterization of proteins affected by DGAT1 overexpression will be required to answer the above questions.
Discrepancy between the studies can be partly explained by the existence of different isoforms of the Amotl1 protein, highlighting the need for further characterization [ 18].
Human growth hormone (hGH) circulates as a mixture of different isoforms.
The identification/characterization of different isoforms of venom toxins, along with the search for natural and synthetic inhibitors, such as monoclonal or polyclonal antibodies, and molecules with different chemical properties, such as heparin, clotting factors, and plant extracts, has increased the possibility of using these agents as more effective therapeutic alternatives.
Moreover, effects of different isoforms were not explored by Kan.
KATP channels composed of different isoform combinations are distributed in different tissues and have distinct pharmacological profiles, which are primarily determined by the identity of associated SUR subunits.
This work reports a combination of X-ray diffraction, surface plasmon resonance experiments and molecular dynamics simulations for the characterization of binders to different isoforms of the cyclophilin (Cyp) protein family.
The specific activity of the different isoforms is still unknown.
A total of four different isoforms belonging to amg-miR156 and three different isoforms belonging to amg-miR159 were discovered.
(A) Relative expression of KAT5, and different isoforms of RNASEH2C in the nascent RNA detected by the Click-iT method.
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