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Our results highlighted the need for a thorough in vitro affinity characterization of candidate IgGs against model animal Fcγ receptors and careful design of preclinical studies.
Then, one can choose the appropriate type of RNAi library to screen (i.e., either genome-wide or for a subset of gene families of interest) and develop robust and reproducible assays for identification, validation, and characterization of candidate genes (Fig. 1A).
Although preliminary data are available [30], [53] [55], further identification and characterization of candidate prostate stem cells and different types of progenitor cells is essential for unraveling prostate development and tumor initiation in mouse models.
The challenges in the next phase of the genetic studies of complex diseases will most likely be overcome by combinatorial approaches based on genetic association and functional characterization of candidate genes located within the intervals identified by GWAS.
Gene ontology characterization of candidate genes at significant loci associated with SCN resistance.
Thus, studies in monkeys are very important for identification and characterization of candidate biomarkers of aging.
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This review also addresses future research challenges relative to the making of new models and their combination to go further in the characterization of candidates and modifier of the DS features.
This paradoxical effect indicates that BRAF inhibitor treatment may be harmful in patients with small BRAF V600E-mutated subclones, underlining the need of accurate characterization of candidates for BRAF inhibitor treatment.
The genetic diversity of new vaccine candidates is generally determined in the preclinical characterization of the candidate.
Strikingly, many of the candidate genes for regulating lipid metabolism had no previously ascribed biological functions; thus, further characterization of these candidate genes is likely to reveal additional regulatory strategies for fat metabolism in mammals.
Dr. Dean's advisers rejected the Bush campaign's characterization of their candidate's appeal.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com