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There are some challenges in investigating these aspects: To generate commensurable data on the abundance of freshwater MP, harmonized monitoring procedures, including sampling, identification, and characterization, are needed.
For this purpose, high-throughput, cost-effective methods for microbiota characterization are needed.
Thus, additional structures and parallel biochemical characterization are needed to establish broader structure activity relationships of START domain proteins.
As a result, metrics based on sensitive and quantitative pre-analytical sample characterization are needed to assess the fraction of template molecules that are competent for PCR amplification.
There is a strong consensus that new integrative tools and approaches for human exposure and risk characterization are needed to significantly advance environmental risk and health impact assessment and health protection (Cohen Hubal et al. 2010; Lioy and Rappaport 2011; National Research Council 2012).
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Their proper biophysical characterization is needed in order to design and control this process.
Normal physiologic mechanisms of annular motion are incompletely understood, and more complete characterization is needed to provide rational basis for annuloplasty ring design and to enhance clinical outcomes.
A variety of treatment options are available but a precise disease characterization is needed: evaluation of cancer location, size, and extent and an indication of tumor aggressiveness.
To understand the real seismic performance of braced frames in moderate seismicity areas, a sound characterization is needed, focusing on behaviour of compression diagonals.
But more-detailed characterization was needed to confirm the connection, so Montagnier sent samples to American virologist Robert C. Gallo, who had contributed to the discovery of the first known human retrovirus (human T-lymphotropic virus) several years earlier.
Our data suggest that the activation of MT can be used in the treatment of seizures, but further pharmacological characterization is needed to understand the anticonvulsant activity of MLT and to design efficient MT-targeting antiepileptic drugs.
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