Sentence examples for characteristics of developing cardiomyocytes from inspiring English sources
There is evidence however, that iPSC-CM have gene expression characteristics of developing cardiomyocytes [7], immature ultrastructural phenotypes [8,9], immature electrophysiological properties [10] and abnormal Ca2+ cycling [11].
The quintessential property of developing cardiomyocytes is their ability to beat spontaneously.
Thus to meet energy and metabolic signaling requirements of developing cardiomyocytes, cardiac differentiation of stem cells is associated with a restructured adenylate kinase transcriptome and proteome.
The Scrib Rac1 interaction plays a crucial role in the organization of developing cardiomyocytes and formation of the ventricular myocardium.
The observations that Rac1 is required for cardiomyocyte alignment in response to mechanical stress, at least in vitro, and that N-cadherin signals via Rac1 to localize connexin-43 in cardiomyocytes, support the idea that Scrib Rac1 signalling may be required for the organization and maturation of the developing cardiomyocytes.
Another recent method for enrichment of cardiomyocytes derived from hESCs or hiPSCs is based on the high abundance of mitochondria in developing cardiomyocytes (Hattori et al. 2010).
The mechanisms underlying spontaneous beating in developing cardiomyocytes are thought to resemble those of adult heart, but have not been directly tested.
Although our data rule out direct interactions with Vangl2 in developing cardiomyocytes, Scrib has been shown to interact with a number of other proteins.
4) NG2 is expressed in developing cardiomyocytes.
We carried out immunohistochemsitry for a range of proteins, including filamentous actin, myosin heavy chain, α-SMA, α-actinin, and cardiac troponin-I, which label developing cardiomyocytes.
