DOI: http://dx.doi.org/10.7554/eLife.06489.002 Endothelial cells (ECs) acquire organ-specific characteristics to adapt to the requirements of their host tissues.
Therefore AGuIX nanoparticles present the characteristics of an adapted drug for theranostic applications: contrast enhancement for MRI due to high relaxivity, high radiosensitizing properties and adapted biodistribution (i.e. elimination by the kidneys and passive accumulation in the tumor).
To describe the design and baseline population characteristics of an adapted lifestyle intervention trial aimed at reducing weight and increasing physical activity in people of Indian and Pakistani origin at high risk of developing type 2 diabetes.
Here we report that under reduced oxygen tensions similar to those that may be encountered in vivo, hypoxia tolerant GBM cells display two additional characteristics of tissues adapted to hypoxia: (1) the stabilization of mitochondria membrane potential and (2) the maintenance of intracellular [ATP].
As reported for Propionibacterium freudenreichii, a related organism with GRAS status used in the manufacture of Swiss cheese, P. acnes has within its genome capability for synthesis and utilisation of polyphosphate and glycogen [ 54], characteristics of bacteria adapted to harsh environments [ 55].
He traveled, often alone, had numerous interesting people enter his life, and learned how to solve his own problems and be independent, even starting a web design company at age 13 -- all characteristics of people who adapt well to change.
We found the following traits that, compared to analogous characteristics of Lambda, specifically adapt Lula/phi80 to survival via horizontal spreading in the laboratory environment by enhancing its stealthy infectivity (qualification number 3) (Fig. 6): A. Preference for lysogeny over lysis upon initial infection, making Lula/phi80 a more temperate phage than Lambda (Fig. 6A).
The proposed scheme is capable of adapting to slow changes in disturbance characteristics, measurement noise characteristics, and plant characteristics.
The architects Le Corbusier and Ludwig Mies van der Rohe exemplified two different ways of adapting Classical stylistic characteristics to modern problems and materials.
