Sentence examples for characteristics clearance from inspiring English sources

In total, matuzumab showed similar PK characteristics (clearance and volumes of distribution) to other therapeutic mAbs following intravenous administration (Mould et al, 1999; Kovarik et al, 2001; Bruno et al, 2005).

Time and concentration dependent characteristics of clearance for these solutes were also demonstrated in PMMA.

The other two studies included the most of patients with favorable characteristics (creatinine clearance more than 60 ml/min and good performance status) [ 21, 22].

In addition four larger phase II studies, Nogue-Aliguer et al reported their results in 41 patients, of whom some, but not all, had unfavorable characteristics (creatinine clearance less than 60 ml/min in 54% of patients and Karnofsky performance status of 70 or less in 37%).

The activation characteristics (included the clearance levels) have been estimated for the different materials/zones of the equatorial plane up to 105 years after plasma operations.

The improved localizing and clearance characteristics of chimeric 81C6 in xenograft model systems suggests that chimeric 81C6 would be an improved reagent for intracompartmental therapy of tenascin-expressing tumors in the human central nervous system.

Surprisingly, despite improving CXCR4 affinity of the ligand, the exchange of DOTA by NOTA had deleterious effects on overall pharmacokinetics, both with respect to CXCR4 targeting efficiency and clearance characteristics.

Its clinical efficacy may result from its unique binding and clearance characteristics and receptor down-regulation mechanisms.

Uraemic toxins are preferentially classified according to the physicochemical characteristics affecting their clearance during dialysis, which is still the main therapeutic option for their removal.

This indicates that the increase in depolarization-induced glutamate release was not the result of altered clearance characteristics in the Tg mice.

In a previous analysis, we reported the pharmacokinetics (PK) of infliximab in patients with AS where certain patients characteristics affecting infliximab clearance were identified [ 9].