Exact(4)
Binomial log link regression analyses were used to investigate the independent effects of each characteristic (ie, age, sex, ethnicity, family history, phenotype, CMA result type) on the presence/absence of a post-CMA medical recommendation.
This included all characteristics in the data quality group, all but one operational characteristic (ie. stability of the system), and just under half of the practical characteristics (Table 1).
Tests for differences in the absolute treatment effect according to each characteristic (ie, tests for interaction) will be derived from standard tests for heterogeneity/trend across subgroups or, where needed, by fitting appropriate interaction terms with treatment allocation in a linear regression model.
An interaction logistic-regression model, in which factors meeting a 0.05 significance level from the main-effect model were retained, was then used to determine how response to belimumab versus placebo varied across different categories within a baseline characteristic (ie, independent treatment-effect modifiers).
Similar(56)
Have student characteristics (ie, gender, country of origin, background) changed?
Two multivariate methods, factorial analysis (FA) and artificial neural network (ANN), were used to investigate the impact of the combined effect of the external phase pH and other parameters (polymer concentration and initial drug load) on MS characteristics; IE, initial drug release, MS size and yield.
The first comprised questions related to practice setting (ie, organisation and hospital) and respondent characteristics (ie, profession and medical specialty).
We used multivariate regressions to control for patient demographics, treatment characteristics (ie, treatment naïve vs experienced, type of ART received) and clinical characteristics (ie, CCI score, concomitant mental disorder, drug and alcohol abuse diagnoses).
Rehabilitation treatment characteristics (ie, treatment form, duration of the treatment and context of rehabilitation) are registered by the counsellor.
Additional neuromuscular characteristics (ie, maximal strength, voluntary activation and twitch properties) are presented in a companion paper.
Model 2 (table 4) permits heterogeneity based on respondents' reported characteristics (ie, respondents' characteristics were taken into account in the analysis).
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