Sentence examples for characterised functions from inspiring English sources

For all genes, and the most similar genes in Arabidopsis, we searched for published data relative to their characterised functions.

SVAs contain sequences with G4 potential, specifically in their CCCTCT hexamer and central VNTR, therefore could show similar properties to already characterised functions of G4 DNA mentioned previously.

Whole-microRNAome and genome analysis of SOX2-silenced hECCs revealed many miRNAs regulated by SOX2, including several with highly characterised functions in both cancer and embryonic stem cell (ESC) biology.

They share a well-conserved hydroxylase domain in their C-terminal halves, whereas the N-terminal halves are more variable and have poorly characterised functions among these three isoforms  [ 20].

Genes with increased expression and well characterised functions include the platelet-derived growth factor family, represented by the PDGFA and PDGFB genes (1.70 and 1.61 fold, respectively) and ECGF1 (1.77 fold).

The best characterised functions of miR-1 are related to the regulation of genes involved in muscle function [29]; in D. melanogaster it is required for post-mitotic growth of larval muscle [30], targeting mRNAs that impair muscle development [28].

Annotation of putative function from unknown sequences is largely based upon sequence homology (similarity) to proteins of known characterised function and particularly the presence of specific sequence/structure motifs (such as the Rossmann fold or the P-loop motif).

Another group consists of proteins with domains of poorly characterised function, such as "unknown" or "general function"; fusion analysis can be used to predict the function of an unknown protein if it is fusion-linked to a partner of known function.

Having established survival of hepatocytes and NPCs in extended (15-day culture), we then characterised phenotypic functions over the time course of culture; this is critical as functioning wanes in 2D and sandwich cultures.

Currently, >30 ADAM proteins have been characterised, exhibiting functions in fertilisation, neurogenesis and cancer.

While the three nucleolar-association groups display vastly different Gene Ontology biological process signatures and evolutionary characteristics, they collectively represent the most well characterised nucleolar functions.