Although a wide spectrum of entities characterised by a monomorphic spindle cell proliferation has been described, there are few general discussions of how monomorphic benign and malignant processes are distinguished histologically.
Conversely, Becattini's MIDs are defined as "socio-territorial entities characterised by the active presence of both a community of people and a population of firms in one naturally and historically bounded area with a dominant industrial activity" (Pyke et al. 1990, cit. in Porter and Ketels 2009 172).
Breast cancer is a heterogeneous disease encompassing a number of distinct entities, characterised by distinct biological features and clinical behaviour.
Sarcoidosis is a systemic entity characterised by the development of non-caseating granulomatous inflammation [22].
Spontaneous omental haemorrhage is a rare entity characterised only in case reports.
Diastolic CHF represents the clinical entity, characterised by signs and symptoms due to increased extravascular water and decreased tissue/organ perfusion, in which patients with CHF have normal or near normal systolic function and significant diastolic dysfunction [10].
IgG4-related disease (IgG4-RD) is a new disease entity characterised by elevated serum IgG4 concentration and/or tissue infiltration by IgG4-positive cells.
Acute on chronic liver failure is a clinically and pathophysiologically distinct entity characterised by the occurrence of hepatic and extra-hepatic organ failures.
Our results support the view that 'classic' Ols' may be a distinct glioma entity characterised by high incidence of 1p/19q loss, limited invasive potential, and the kinetic profile of in situ proliferating, relatively circumscribed tumours.
These criteria are the basis of the definition of IBC set forth by the American Joint Committee on Cancer (AJCC) as 'a clinicopathological entity characterised by diffuse erythema and oedema of the breast, often without an underlying palpable mass' (AJCC, 2002).
26 A recent conference defined cognitive frailty as a clinical entity characterised by cognitive impairment related to physical causes with potential reversibility, 27 making it a useful target for the secondary prevention of cognitive problems in older people.
