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The degree of drug-induced G6PD deficiency related haemolysis depends on a number of factors including the G6PD variant, the drug and dosage, and poorly characterised disease factors.
Male breast cancer (MBC) is an infrequent and poorly characterised disease.
A number of informative studies have characterised disease progression using radiography and magnetic resonance imaging (MRI) [ 4, 5] but such modalities can only inform on gross structural changes.
For comparison, a previously characterised disease stage-matched series of younger (<70 years) patients (N=1809) was retrieved from the unit's database (Abd et-Rehim et al, 2005; Rakha et al, 2008; Aleskandarany et al, 2011).
It has a well characterised disease cycle, is amenable to culture in the laboratory, and has recently been transformed via ATMT [16].
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An alternative approach could be to characterise disease progression using an alternative concept, such as dependence, or a multi-domain model of disease progression [50, 51].
Alternative ways of characterising disease progression, such as dependence and health state utilities, should also be given consideration in future research.
Models of infectious disease increasingly seek to incorporate heterogeneity of social interactions to more accurately characterise disease spread.
Our work highlights the importance of temperature changes, rather than defined thresholds, when characterising disease resistance mechanisms in wheat.
Therefore, sCD25 has been used as a biomarker to help characterise disease progression, prognosis and treatment [ 23– 25].
A major goal in the post-genomic era is to identify and characterise disease susceptibility genes and to apply this knowledge to disease prevention and treatment.
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